District 4 is bounded on nearly every side by water — the Sài Gòn River, the Bến Nghé canal, the Tẻ canal — a geography that shaped both its economy and its reputation for a century and a half.
Nguyễn Hữu Cảnh establishes Gia Định prefecture. The hamlets that will become District 4 — Khánh Hội, Vĩnh Hội, Cây Bàng, Xóm Chiếu, and the islet of Nguyễn Kiệu — already exist under a string of older names: Tam Hội, Khánh Hòa, Khánh Bình, Bình Ý, Tân Vĩnh.
Construction begins on the headquarters of the Messageries Impériales shipping line at the mouth of the Bến Nghé canal — a building whose dragon-topped roofline will earn it the name Bến Nhà Rồng, "Dragon House Wharf." It's completed the following year.
As the Port of Saigon grows into the busiest in French Indochina, Khánh Hội fills with hamlets of dockworkers and shipyard laborers — the beginning of a working-class identity that will define the district for the next hundred years.
A young man calling himself Văn Ba boards the French steamer Amiral Latouche-Tréville at Bến Nhà Rồng, working as a galley hand. His name was Nguyễn Tất Thành — he would later be known as Hồ Chí Minh. See Anecdotes, below.
The name "District 4" (Quận 4) is formally adopted for the area, after decades in which it was known mainly by its constituent neighborhoods — Xóm Chiếu and Khánh Hội above all.
Khánh Hội street is cut through the district after the clearance of riverside slum housing, becoming one of District 4's three main arteries.
District authorities formally launch Vĩnh Khánh food street, turning what was already an organic cluster of seafood stalls into an official destination — see Where to eat, below.
A citywide ward reform merges District 4's ten wards into three: Vĩnh Hội, Khánh Hội and Xóm Chiếu — names lifted directly from the district's oldest hamlets.